Title:
有機化合物
Document Type and Number:
Japanese Patent JP5298022
Kind Code:
B2
Abstract:
The present invention provides compounds of the following structure; A-L1-B—C-D that are useful for treating or preventing conditions or disorders associated with DGAT1 activity in animals, particularly humans.
Inventors:
Sun Moje
Gary Mark Coppola
Yeon Taeyeon
Thomas A. Gilmore
Gary Mark Coppola
Yeon Taeyeon
Thomas A. Gilmore
Application Number:
JP2009533499A
Publication Date:
September 25, 2013
Filing Date:
October 17, 2007
Export Citation:
Assignee:
Novartis Age
International Classes:
C07D209/10; A61K31/404; A61K31/4184; A61K31/422; A61K31/423; A61K31/428; A61K31/437; A61K31/4439; A61K31/4709; A61K31/4725; A61K31/496; A61K31/497; A61K31/498; A61K31/501; A61K31/506; A61K31/5377; A61P1/14; A61P1/16; A61P1/18; A61P3/04; A61P3/06; A61P3/10; A61P9/00; A61P9/08; A61P9/10; A61P9/12; A61P17/10; A61P19/06; A61P35/00; A61P43/00; C07D235/18; C07D263/56; C07D401/12; C07D401/14; C07D403/12; C07D405/12; C07D409/12; C07D413/12; C07D417/12; C07D513/04
Domestic Patent References:
| JP2004520834A | ||||
| JP2003503400A | ||||
| JP2004511466A | ||||
| JP2005506349A | ||||
| JP61246161A | ||||
| JP2000095767A | ||||
| JP2005525389A | ||||
| JP2009526034A |
Foreign References:
| WO2004072025A1 | ||||
| WO2006099379A1 | ||||
| WO2004017997A1 | ||||
| WO2003106439A1 | ||||
| US3551443 | ||||
| WO2005108370A1 | ||||
| WO2007043653A1 |
Other References:
Goker, Hakan; Kus, Canan; Boykin, David W.; Yildiz, Sulhiye; Altanlar, Nurten,Synthesis of some new 2-substituted-phenyl-1H-benzimidazole-5- carbonitriles and their potent activity against Candida species,Bioorganic and Medicinal Chemistry ,2002年,10(8),2589-2596
Bedair, A. H.; Aly, F. M.; Hassan, M. F. A.,Synthesis of some derivatives of 4-(acetylamino)-3-nitrobenzenesulfonic acid. Part 2,Acta Pharmaceutica Jugoslavica,1987年,37(3),157-63
Evans, D.; Hicks, T. A.; Williamson, W. R. N.; Dawson, W.; Meacocok S. C. R.; Kitchen, E. A.,Synthesis of a group of 1H-benzimidazoles and their screening for antiinflammatory activity,European Journal of Medicinal Chemistry,1996年,31(7-8),635-642
Goeker, Hakan; Tebrizli, Emin; Abbasoglu, Ufuk,Synthesis of 1,2-disubstituted benzimidazole-5(6)-carboxamides and evaluation of their antimicrobial activity,Farmaco,1996年,51(1),53-8
Gao, Fanghua; Huang, Lixin,Antihydatidosis drugs: synthesis of benzimidazoles,Zhongguo Yiyao Gongye Zazhi,1989年,20(3),110-15
Richards, Mark L.; Lio, Shirley Cruz; Sinha, Anjana; Banie, Homayon; Thomas, Richard J.; Major, Michael; Tanji, Mark; Sircar, Jagadish C.,Substituted 2-phenyl-benzimidazole derivatives: novel compounds that suppress key markers of allergy,European Journal of Medicinal Chemistry ,2006年,41(8),950-969
Carsten Behrens,; Niels Harrit,; peter E. Nielsen,Synthesis of a Hoechst 32258 Analogue Amino Acid Building Block for Direct Incorporation of a Fluorescent, High-Affinity DNA Binding Motif into Peptides,Bioconjugate Chemistry,2001年,12(6),1021-1027
Hakan Goker,; Meral Tuncbilek,; Sibel Suzen,; Canan Kus,; Nurten Altanlar ,Synthesis and antimicrobial activity of some new 2-Phenyl-N-substituted Carboxamide-1H-benzimidazole Derivatives,Archiv Der Pharmazie,2001年,334,148-152
Bedair, A. H.; Aly, F. M.; Hassan, M. F. A.,Synthesis of some derivatives of 4-(acetylamino)-3-nitrobenzenesulfonic acid. Part 2,Acta Pharmaceutica Jugoslavica,1987年,37(3),157-63
Evans, D.; Hicks, T. A.; Williamson, W. R. N.; Dawson, W.; Meacocok S. C. R.; Kitchen, E. A.,Synthesis of a group of 1H-benzimidazoles and their screening for antiinflammatory activity,European Journal of Medicinal Chemistry,1996年,31(7-8),635-642
Goeker, Hakan; Tebrizli, Emin; Abbasoglu, Ufuk,Synthesis of 1,2-disubstituted benzimidazole-5(6)-carboxamides and evaluation of their antimicrobial activity,Farmaco,1996年,51(1),53-8
Gao, Fanghua; Huang, Lixin,Antihydatidosis drugs: synthesis of benzimidazoles,Zhongguo Yiyao Gongye Zazhi,1989年,20(3),110-15
Richards, Mark L.; Lio, Shirley Cruz; Sinha, Anjana; Banie, Homayon; Thomas, Richard J.; Major, Michael; Tanji, Mark; Sircar, Jagadish C.,Substituted 2-phenyl-benzimidazole derivatives: novel compounds that suppress key markers of allergy,European Journal of Medicinal Chemistry ,2006年,41(8),950-969
Carsten Behrens,; Niels Harrit,; peter E. Nielsen,Synthesis of a Hoechst 32258 Analogue Amino Acid Building Block for Direct Incorporation of a Fluorescent, High-Affinity DNA Binding Motif into Peptides,Bioconjugate Chemistry,2001年,12(6),1021-1027
Hakan Goker,; Meral Tuncbilek,; Sibel Suzen,; Canan Kus,; Nurten Altanlar ,Synthesis and antimicrobial activity of some new 2-Phenyl-N-substituted Carboxamide-1H-benzimidazole Derivatives,Archiv Der Pharmazie,2001年,334,148-152
Attorney, Agent or Firm:
Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Masayuki Nakagawa
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Masayuki Nakagawa