Title:
ORGANOIDS COMPRISING DECELLULARIZED AND REPOPULATED PLACENTAL VASCULAR SCAFFOLD
Document Type and Number:
Japanese Patent JP2023015063
Kind Code:
A
Abstract:
To provide organoids comprising or consisting of a decellularized placental vascular scaffold, and methods of making and using the same.SOLUTION: The present invention provides an organoid, comprising one or more types of cells, and comprising decellularized placental vascular scaffold, wherein the organoid performs at least one function of an organ, or a tissue from an organ, wherein the at least one function of an organ or tissue from an organ is production of a protein, growth factor, cytokine, interleukin, or small molecule characteristic of at least one cell type from the organ or tissue; and wherein the decellularized placental vascular scaffold comprises substantially intact placental vasculature matrix.SELECTED DRAWING: Figure 1
Inventors:
Mohit Bee Buhatia
Robert Jay Hariri
Wolfgang Hofgartner
Jia-Lun Wang
Kian Yi
Robert Jay Hariri
Wolfgang Hofgartner
Jia-Lun Wang
Kian Yi
Application Number:
JP2022165987A
Publication Date:
January 31, 2023
Filing Date:
October 17, 2022
Export Citation:
Assignee:
Cellularity ink.
International Classes:
C12N5/071; A61K35/12; A61K35/22; A61K35/30; A61K35/39; A61K35/407; A61K35/50; A61K35/51; A61K35/54; A61K35/55; A61P1/14; A61P1/18; A61P3/00; A61P3/10; A61P5/00; A61P5/02; A61P5/06; A61P5/14; A61P5/18; A61P5/24; A61P5/38; A61P5/40; A61P5/48; A61P5/50; A61P7/00; A61P7/02; A61P7/04; A61P9/00; A61P13/02; A61P13/12; A61P15/08; A61P15/10; A61P19/10; A61P21/00; A61P25/18; A61P25/20; A61P25/28; A61P43/00; C12N5/0735; C12N5/0775; C12N5/0783; C12N5/0784; C12N5/0797; C12N5/10
Attorney, Agent or Firm:
Toru Ishikawa
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