Title:
オキサゾールヒドロキサム酸誘導体及びその使用
Document Type and Number:
Japanese Patent JP5278653
Kind Code:
B2
Abstract:
Provided are an oxazole hydroxamic acid derivatives and pharmaceutically useful salt thereof as a histone deacetylase inhibitor. The oxazole hydroxamic acid derivative and pharmaceutically useful salt thereof, prepared in accordance with the present invention, can treat and/or prevent various cancers and inflammatory diseases caused by histone deacetylase.
Inventors:
Cho, John-Woo
Rim, Saint-Chur
Men, Chulu-Jung
Won, Seung-Wan
Bae Sun-jin
Kim, Eun-E
Rim, Saint-Chur
Men, Chulu-Jung
Won, Seung-Wan
Bae Sun-jin
Kim, Eun-E
Application Number:
JP2007551199A
Publication Date:
September 04, 2013
Filing Date:
January 13, 2006
Export Citation:
Assignee:
SK by Offer Masticals Company Limited
International Classes:
C07D263/32; A61K31/421; A61K31/4439; A61P29/00; A61P35/00; A61P37/06; A61P43/00; C07D413/04
Domestic Patent References:
| JP2004250401A | ||||
| JP2002097189A |
Other References:
日本化学会 編,新実験化学講座14 有機化合物の合成と反応II,丸善株式会社,1977年,p.763-765
DAI,Y. et al.,A novel series of histone deacetylase inhibitors incorporating hetero aromatic ring systems as connection units,Bioorganic & Medicinal Chemistry Letters,2003年,Vol.13, No.21,p.3817-3820
DAI,Y. et al.,A novel series of histone deacetylase inhibitors incorporating hetero aromatic ring systems as connection units,Bioorganic & Medicinal Chemistry Letters,2003年,Vol.13, No.21,p.3817-3820
Attorney, Agent or Firm:
Calyx
Miyazaki Yoshio
Tsutomu Kato
Companion wisdom
Miyazaki Yoshio
Tsutomu Kato
Companion wisdom