ＰＤＧＦおよびＶＥＧＦ結合アプタマー、および、ＰＤＧＦおよびＶＥＧＦが介在する病気の治療へのそれらの使用

Title:

ＰＤＧＦおよびＶＥＧＦ結合アプタマー、および、ＰＤＧＦおよびＶＥＧＦが介在する病気の治療へのそれらの使用

Document Type and Number:

Japanese Patent JP6587934

Kind Code:

B2

Abstract:

Aptamers that bind PDGF and aptamers that bind VEGF are provided. In addition, aptamer constructs comprising a PDGF aptamer and a VEGF aptamer are provided. Pharmaceutical compositions comprising the aptamers and aptamer constructs are provided, as well as methods of treating conditions using the aptamers and aptamer constructs.

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Inventors:

Jarvis, Thale Sea
Rolov, John Sea
Gerinas, Amy Dee
Chan, Chi
Doloré, Daniel W
War, Sheila M
Janjik, nevoisha

Application Number:

JP2015503617A

Publication Date:

October 09, 2019

Filing Date:

March 28, 2013

Export Citation:

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Assignee:

SomaLogic, Inc.

International Classes:

C12N15/115; A61K31/7088; A61K48/00; A61P27/02

Domestic Patent References:

JP2006516151A
JP2007525177A
JP2004533861A

Foreign References:

WO2005052121A1
WO2006050498A1
WO2011130195A1

Other References:

Proc. Natl. Acad. Sci. USA,2012年12月 4日,Vol. 109, No. 49,p. 19971-19976

Attorney, Agent or Firm:

Shinjiro Ono
Osamu Yamamoto
Toru Miyamae
Motoharu Nakanishi
Akiko Nakahama

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