Title:
医薬のためのプラットフォームとしての、少なくとも1つの保護されたチオール領域を有するPEG-アルブミン組成物
Document Type and Number:
Japanese Patent JP2012522782
Kind Code:
A
Abstract:
This composition comprises a polyethylene glycol-albumin composition having at least one protected thiol region wherein the composition comprises PEG-AlbCys34 with Cys-34 preserved as a thiol. The albumin is linked to medications such as, antioxidants with a reduced sulfhydryl group through the Cys 34 residing on the albumin. The compositions are useful in treating patients.
Inventors:
Asari, Rageb
Digman, john david
Shapiro, Joseph Eye.
Digman, john david
Shapiro, Joseph Eye.
Application Number:
JP2012503428A
Publication Date:
September 27, 2012
Filing Date:
April 02, 2010
Export Citation:
Assignee:
The University of Toledo
International Classes:
A61K47/48; A61K31/198; A61K31/436; A61K31/5585; A61K33/24; A61K38/00; A61K38/22; A61K47/34; A61K47/42; A61P39/06
Attorney, Agent or Firm:
Yoshiyuki Kawaguchi
Hidemi Matsukura
Shinichi Sanuki
Takeshi Niwa
Hidemi Matsukura
Shinichi Sanuki
Takeshi Niwa