Title:
PI-3キナーゼインヒビターおよびそれらの使用方法
Document Type and Number:
Japanese Patent JP2009530233
Kind Code:
A
Abstract:
Phosphatidylinositol (PI) 3 kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, phospholipid kinases, G-protein coupled receptors, and phosphatases.
Inventors:
Nee, Chi-Chie
Petch, Sabina
Burger, matthew
Han, Woo Suk
Smith, aaron
Atara, Godana
Barthuris, Sara
Fraser, Kelly
Joel, Verhaygen
Chang, Yangcheng
Ivano Wicks, Ed
Hendrickson, Tom
Nap, mark
Merit, hanne
Bolivar, Charles
Wiseman, Marion
Le Grand, Darren Mark
Bruce, Ian
Dale, james
Orchid, thion
Rubin, Barry
Costares, Ablanc
Liu, Chie
Pick, teresa
Menezes, daniel
Petch, Sabina
Burger, matthew
Han, Woo Suk
Smith, aaron
Atara, Godana
Barthuris, Sara
Fraser, Kelly
Joel, Verhaygen
Chang, Yangcheng
Ivano Wicks, Ed
Hendrickson, Tom
Nap, mark
Merit, hanne
Bolivar, Charles
Wiseman, Marion
Le Grand, Darren Mark
Bruce, Ian
Dale, james
Orchid, thion
Rubin, Barry
Costares, Ablanc
Liu, Chie
Pick, teresa
Menezes, daniel
Application Number:
JP2008555474A
Publication Date:
August 27, 2009
Filing Date:
February 14, 2007
Export Citation:
Assignee:
Novartis Age
International Classes:
C07D417/04; A61K31/444; A61K31/4545; A61K31/496; A61K31/497; A61K31/5025; A61K31/506; A61K31/5377; A61P1/00; A61P1/04; A61P3/04; A61P3/10; A61P9/10; A61P11/00; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P31/04; A61P37/06; A61P37/08; A61P43/00; C07D417/14; C07D471/04; C07D487/04
Domestic Patent References:
| JP2003521543A | 2003-07-15 | |||
| JP2004518684A | 2004-06-24 |
Foreign References:
| WO2004076412A2 | 2004-09-10 | |||
| WO2005035526A1 | 2005-04-21 | |||
| WO2008016131A1 | 2008-02-07 | |||
| WO2005089763A1 | 2005-09-29 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita