Title:
PROTAC抗体コンジュゲート及び使用方法
Document Type and Number:
Japanese Patent JP2019522633
Kind Code:
A
Abstract:
本明細書に記載される主題は、抗体−PROTACコンジュゲート(PAC)、それらを含有する薬学的組成物、ならびに標的タンパク質分解が有益である疾患及び病態の治療におけるそれらの使用に向けられる。【選択図】なし
Inventors:
Pillow, thomas
Jack, sudowski
Riven, Staben
Stephen, Stephen
Way, binchin
Welts, Ingrid
Adikali, Praga
Brachiere, Nicole
Dragovich, Peter
Fair brother, wayne
Jack, sudowski
Riven, Staben
Stephen, Stephen
Way, binchin
Welts, Ingrid
Adikali, Praga
Brachiere, Nicole
Dragovich, Peter
Fair brother, wayne
Application Number:
JP2018560504A
Publication Date:
August 15, 2019
Filing Date:
May 19, 2017
Export Citation:
Assignee:
Genentech, Incorporated
International Classes:
C07D243/14; A61K31/454; A61K31/496; A61K31/5513; A61K45/00; A61K47/68; A61P7/00; A61P9/10; A61P17/00; A61P19/02; A61P25/00; A61P29/00; A61P35/00; A61P35/02; A61P37/06; A61P43/00
Domestic Patent References:
JP2017529345A | 2017-10-05 |
Foreign References:
WO2014165506A1 | 2014-10-09 | |||
US20160045607A1 | 2016-02-18 | |||
WO2014044622A1 | 2014-03-27 | |||
WO2015071393A1 | 2015-05-21 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita