Title:
ＰＳＭＡ結合剤及びその使用
Document Type and Number:
Japanese Patent JP7219497
Kind Code:
B2
Abstract:
Prostate-specific membrane antigen (PSMA) binding compounds having radioisotope substituents are described, as well as chemical precursors thereof. Compounds include pyridine containing compounds, compounds having phenylhydrazine structures, and acylated lysine compounds. The compounds allow ready incorporation of radionuclides for single photon emission computed tomography (SPECT) and positron emission tomography (PET) for imaging, for example, prostate cancer cells and angiogenesis.
Inventors:
pumper martin gilbert
Mes Ronnie Charles
Chen Inn
Mes Ronnie Charles
Chen Inn
Application Number:
JP2021012046A
Publication Date:
February 08, 2023
Filing Date:
January 28, 2021
Export Citation:
Assignee:
The Johns Hopkins University
International Classes:
A61K31/44; A61K31/197; A61K51/04; A61P35/00; C07B59/00; C07D213/61; C07D213/81; C07D213/82
Domestic Patent References:
| JP5588441B2 | ||||
| JP5806765B2 | ||||
| JP6030724B2 |
Foreign References:
| WO2008058192A2 |
Attorney, Agent or Firm:
Shinichiro Tanaka
Yoshi Kazuhiko Ta
Hiroyuki Suda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Yoshi Kazuhiko Ta
Hiroyuki Suda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori