Title:
ヘテロアリールトシラートおよびヘテロアリールベンゼンスルホナートを用いる末端アルキンのパラジウム触媒によるカップリング法
Document Type and Number:
Japanese Patent JP5530924
Kind Code:
B2
Abstract:
A process for the palladium-catalyzed coupling of terminal alkynes with heteroaryl tosylates and heteroaryl benzenesulfonates The present invention relates to a process for the regioselective synthesis of compounds of the formula (I), wherein D, J and W have the meanings indicated in the claims. The present invention provides an efficient and general palladium-catalyzed coupling process of heteroaryl tosylates with terminal alkynes to a wide variety of substituted, multifunctional heteroaryl-1-alkynes of the formula I.
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Inventors:
Omar Rukaik
Marc Nazareth
Andreas Lindenschmidt
Jorge Alonso
Matthias Ullman
Nis Haarland
Marc Nazareth
Andreas Lindenschmidt
Jorge Alonso
Matthias Ullman
Nis Haarland
Application Number:
JP2010513725A
Publication Date:
June 25, 2014
Filing Date:
June 19, 2008
Export Citation:
Assignee:
SANOFI
International Classes:
C07D213/16; C07D213/26; C07D213/30; C07D215/12; C07D215/14; C07D231/12; C07D231/56; C07D239/26; C07D333/38; C07D409/06; C07D471/04; C07B61/00
Foreign References:
| WO2007061882A1 | ||||
| WO2005103002A1 |
Other References:
ROLLET, PATRICK,JOURNAL OF MOLECULAR CATALYSIS A: CHEMICAL,2005年,V241 N1-2,P39-51
DJAKOVITCH, LAURENT,ADVANCED SYNTHESIS & CATALYSIS,2004年,V346 N13-15,P1782-1792
DJAKOVITCH, LAURENT,ADVANCED SYNTHESIS & CATALYSIS,2004年,V346 N13-15,P1782-1792
Attorney, Agent or Firm:
Junji Yuda
Shoji Miwa
Noriyuki Takebayashi
Shoji Miwa
Noriyuki Takebayashi