Title:
PARAHERQUAMIDE AND DIHYDROPARAHERQUAMIDE AS ANTIPARASITIC
Document Type and Number:
Japanese Patent JPS6461418
Kind Code:
A
Abstract:
PURPOSE: To obtain the subject composition effective for preventing and treating parasitic infection of endoparasite and ectoparasite, comprising paraherquamide or dihydroparaherquamide as an active ingredient. CONSTITUTION: This composition comprises paraherquamide of formula I or dihydroparaherquamide of formula II or their mixture as an active ingredient. The compounds show activity as antiparasitic agent for parasite of endoparasite and ectoparasite, against parasite, especially vermes, ectoparasite and parasite infecting animal and plant such as insect, acarid mite and human body. The content of the active ingredient is 0.001-0.5wt.% in the case of liquid medicine, 0.005-5% in the case of parenteral administration medicine, 0.00001-0.002wt.% in the case of feed preparation, 0.005-2wt.% in the case of food premix and 0.0002-0.5wt.% in the case of supplement. The compound is obtained by culturing Penicillium charlesii MF5,120 (ATCC 20,841) as a new fungus and its variant.
Inventors:
MARIA TEE DEE MATASU
DAN EE OSUTORINDO
RUISU PUNSORA
SAGURARIO MOHARESU DERU BUARU
DAN EE OSUTORINDO
RUISU PUNSORA
SAGURARIO MOHARESU DERU BUARU
Application Number:
JP18955488A
Publication Date:
March 08, 1989
Filing Date:
July 28, 1988
Export Citation:
Assignee:
MERCK & CO INC
International Classes:
A61K31/495; A61K31/55; A61P33/00; C07D491/22; C12N1/14; C12P17/18; A23K20/195; C12R1/80; (IPC1-7): A23K1/17; A61K31/495; C07D491/22; C12N1/14; C12P17/18
Attorney, Agent or Firm:
Masao Okabe (2 outside)