PD-1/PD-L1 INHIBITORS - GILEAD SCIENCES INC

Title:

PD-1/PD-L1 INHIBITORS

Document Type and Number:

Japanese Patent JP2022116244

Kind Code:

A

Abstract:

To provide compounds useful as inhibitors of PD-1, PD-L1 or the PD-1/PD-L1 interaction, useful for treatment of cancer.SOLUTION: The invention provides a compound illustrated by the formula in the figure, or a pharmaceutically acceptable salt, stereoisomer, stereoisomer mixture, solvate or tautomer thereof.SELECTED DRAWING: None

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Inventors:

EVANGELOS AKTOUDIANAKIS
TODD APPLEBY
CHO AESOP
DU ZHIMIN
MICHAEL GRAUPE
JUAN A GUERRERO
SALMAN Y JABRI
LATESHKUMAR THAKORLAL LAD
PAULO A MACHICAO TELLO
JONATHAN WILLIAM MEDLEY
SAMUEL E METOBO
PRASENJIT KUMAR MUKHERJEE
DEVAN NADUTHAMBI
GREGORY NOTTE
ERIC Q PARKHILL
BARTON W PHILLIPS
SCOTT PRESTON SIMONOVICH
NEIL H SQUIRES
CHANDRASEKAR VENKATARAMANI
WANG PEIYUAN
WATKINS WILLIAM J
XU JIE
YANG KIN SHING
CHRISTOPHER ALLEN ZIEBENHAUS

Application Number:

JP2022088597A

Publication Date:

August 09, 2022

Filing Date:

May 31, 2022

Export Citation:

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Assignee:

GILEAD SCIENCES INC

International Classes:

A61K31/137; C07D213/69; A61K31/197; A61K31/198; A61K31/277; A61K31/341; A61K31/397; A61K31/40; A61K31/4025; A61K31/404; A61K31/4184; A61K31/427; A61K31/428; A61K31/437; A61K31/44; A61K31/4427; A61K31/443; A61K31/4436; A61K31/4439; A61K31/444; A61K31/4545; A61K31/4709; A61K31/496; A61K31/497; A61K31/498; A61K31/506; A61K31/517; A61K31/5377; C07C217/58; C07C229/14; C07C229/22; C07C255/54; C07C255/59; C07C317/14; C07D207/12; C07D207/267; C07D209/08; C07D213/64; C07D213/71; C07D213/82; C07D213/84; C07D213/85; C07D235/12; C07D277/24; C07D277/64; C07D295/088; C07D307/12; C07D401/04; C07D401/12; C07D401/14; C07D403/14; C07D405/12; C07D405/14; C07D409/12; C07D409/14; C07D413/10; C07D413/12; C07D413/14; C07D417/12; C07D417/14; C07D453/00; C07D453/02; C07D471/04; C07D471/10; C07D487/04; C07D487/10; C07D519/00

Attorney, Agent or Firm:

Shusaku Yamamoto
Morishita Natsuki

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