Title:
ペニシリン結晶及びその製造法
Document Type and Number:
Japanese Patent JP3743822
Kind Code:
B2
Abstract:
The crystal of the invention is crystal of diphenylmethyl 2-methyl-2-triazolylmethylpenam-3-carboxylate which is stable substantially without decomposition or degradation of properties even when left to stand at room temperature for 1 year. The crystal of the invention can be prepared by a process comprising the steps of concentrating a solution containing diphenylmethyl 2-methyl-2-triazolylmethylpenam-3-carboxylate represented by the formula (2)wherein Ph is a phenyl group, diluting the concentrate with acetic ester and mixing the diluted solution with hexane or a solvent mixture of hexane and acetic ester to crystallize the diphenylmethyl 2-methyl-2-triazolylmethylpenam-3-carboxylate.
Inventors:
Akihiro Shimabayashi
Ichiro Kawahara
Ichiro Kawahara
Application Number:
JP2000244288A
Publication Date:
February 08, 2006
Filing Date:
August 11, 2000
Export Citation:
Assignee:
Otsuka Chemical Holdings Co., Ltd.
Taiho Pharmaceutical Co., Ltd.
Taiho Pharmaceutical Co., Ltd.
International Classes:
C07D499/00; A61P31/04; C07D499/18; C07D499/44; C07D499/86; C07D499/87; C07D499/897
Domestic Patent References:
| JP1132588A | ||||
| JP1135787A | ||||
| JP64006283A | ||||
| JP64042486A | ||||
| JP8505645A |
Attorney, Agent or Firm:
Eiji Saegusa
Kakehi Yuro
Takeshi Ohara
Hiroji Nakagawa
Yasumitsu Tate
Kenji Saito
Jun Fujii
Hitoshi Seki
Mutsuko Nakano
Kakehi Yuro
Takeshi Ohara
Hiroji Nakagawa
Yasumitsu Tate
Kenji Saito
Jun Fujii
Hitoshi Seki
Mutsuko Nakano
Previous Patent: CLOCK SWITCHER AND RECORDING MEDIUM
Next Patent: PENICILLIN CRYSTAL AND METHOD FOR MANUFACTURING THE SAME
Next Patent: PENICILLIN CRYSTAL AND METHOD FOR MANUFACTURING THE SAME