Title:
PENICILLIN DERIVATIVE, MANUFACTURE AND MEDICINAL COMPOSITION
Document Type and Number:
Japanese Patent JPS58983
Kind Code:
A
Abstract:
A compound of formula (I) or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof: wherein R is phenyl, 4-hydroxyphenyl, 2- or 3-thienyl, cyclohexyl, cyclohexan-1-yl, cyclohexa-1,4-dien-1-yl, or 3,4-disubstituted phenyl wherein the substituents may be the same or different and are selected from chlorine, hydroxy and methoxy; and R<1> represents hydrogen, an alkyl, alkenyl, cycloalkyl or cycloalkenyl group, an optionally substituted phenyl, a cyclopropyl alkyl group, a hydroxy group optionally substituted by alkyl, alkenyl, cycloalkyl, phenyl or benzyl, an optionally substituted mercapto group, an alkylsulphenyl group, a free or substituted amino group, an optionally substituted piperazino or phenylalkylamino group, an acylamino group or an alkyl, aralkyl or arylsulphonyl amino group.
Inventors:
MAIKERU JIYON DORAIBAA
ANDORIYUU UIRIAMU TEIRAA
ANDORIYUU UIRIAMU TEIRAA
Application Number:
JP10127882A
Publication Date:
January 06, 1983
Filing Date:
June 12, 1982
Export Citation:
Assignee:
BEECHAM GROUP LTD
International Classes:
C07D499/66; A61K31/43; A61P31/04; C07D239/48; C07D499/00; C07D499/64; C07D499/68; C07D499/70; (IPC1-7): A61K31/43; C07D499/64; C07D499/68
Attorney, Agent or Firm:
Akizawa Masamitsu