Title:
PENICILLIN ESTERS AND THEIR PREPARATIONS AND MEDICAL COMPOSITIONS CONTAINING SAME
Document Type and Number:
Japanese Patent JPS5419993
Kind Code:
A
Abstract:
A class of esters of the penicillin, nafcillin have the general formula: wherein A is a C1-C6 alkylene group substituted with one or two groups of formula -NR1 R2 and optionally further substituted with one or more methyl or ethyl groups, wherein R1 and R2 are the same or different and each is a C1-C6 alkyl group or R1 and R2 together with the nitrogen atom to which they are attached form a saturated 5- or 6- membered heterocyclic ring. Upon oral administration, the esters are absorbed into the bloodstream where they are hydrolyzed to release the antibacterially active parent penicillin, nafcillin.
Inventors:
HARII FUERESU
Application Number:
JP8526878A
Publication Date:
February 15, 1979
Filing Date:
July 14, 1978
Export Citation:
Assignee:
BEECHAM GROUP LTD
International Classes:
A61K31/43; A61P31/04; C07D499/00; C07D499/74; (IPC1-7): A61K31/43; C07D499/48