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Title:
PEPTIDE FOR DIAGNOSIS OF AIDS
Document Type and Number:
Japanese Patent JPH01153700
Kind Code:
A
Abstract:

NEW MATERIAL: A synthesized peptide expressed by formula I and formula II.

USE: Reagent for detection of anti-lymphadenopathy-associated virus(LAV)/human T-lymphadenopathy virus III (HTLVIII) antibody. Diagnostic drug of acquired immunodeficiency syndromes(AIDS).

PREPARATION: For example, a p-benzyloxyalcohol resin is used as a solid phase carrier, on which amino acids with protected amino groups from the C-terminal end according to the amino acid sequence of the peptides are allowed to react in the presence of a condensing agent such as N,N'- dicylohexylcarbodiimide or the like, and then the amino-protective groups are removed. This process is repeated to obtain the peptide resin ester. The obtd. ester is treated with trifluoroacetic acid to detach the peptide from the resin and to remove all protective groups. Thus, the peptides expressed by formula I or formula II can be obtd.


Inventors:
FURANSESUKO BERINI
JIERUBESU DEIONNU
MAASHIYARU RAKUROWA
Application Number:
JP30552087A
Publication Date:
June 15, 1989
Filing Date:
December 02, 1987
Export Citation:
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Assignee:
IAF BIOCHEM INT
International Classes:
C07K19/00; C07K7/08; C07K14/00; C07K17/08; G01N33/569; (IPC1-7): C07K7/08; C07K15/12; C07K17/08; C07K99/00; G01N33/569
Attorney, Agent or Firm:
Akira Asamura (2 outside)