Title:
Peptidyl arginine day Minase 1 in an outer skin and/or 3 Acty beta compound, and its use
Document Type and Number:
Japanese Patent JP6049691
Kind Code:
B2
Abstract:
The present invention relates to the activation of peptidyl arginine deiminase (PADs) 1 and/or 3 in the epidermis by at least one active agent used alone or in combination, namely caffeine, acefylline and/or theobromine in a cosmetic and/or pharmaceutical composition. The present invention also relates to the use of the aforementioned active agents in cosmetics and/or therapeutics, alone or in combination, in order to improve the barrier functions of the epidermis, to prevent and/or treat symptoms related to dry skin or to improve and/or promote hydration of the keratinous layer. Finally, the invention relates to increasing the activity of PAD1 and/or PAD3 in the epidermis.
Inventors:
Helene, Duplan
Silvie, Donu-Marion
Stefanu, Pwanee
Marie-Claire, Mechan
Ghee, sale
Michelle, Simon
Silvie, Donu-Marion
Stefanu, Pwanee
Marie-Claire, Mechan
Ghee, sale
Michelle, Simon
Application Number:
JP2014504305A
Publication Date:
December 21, 2016
Filing Date:
April 11, 2012
Export Citation:
Assignee:
PIERRE FABRE DERMO-COSMETIQUE
International Classes:
A61K8/49; A61K31/522; A61P17/06; A61P17/16; A61P37/08; A61Q19/00
Domestic Patent References:
| JP8291018A | ||||
| JP2009508850A | ||||
| JP2009500394A | ||||
| JP2002080323A | ||||
| JP2003335630A | ||||
| JP2005314367A | ||||
| JP2006213696A |
Foreign References:
| US20020150597 | ||||
| GB2221391A |
Attorney, Agent or Firm:
Hirohito Katsunuma
Yukitaka Nakamura
Noritaka Yokota
Hiroshi Sorimachi
Yukitaka Nakamura
Noritaka Yokota
Hiroshi Sorimachi
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