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Title:
PERORAL LIQUID COMPOSITION CONTAINING SULFODEHYDROABIETIC ACID HAVING ADJUSTED PARTICLE SIZE AND REDUCED IN BITTER TASTE
Document Type and Number:
Japanese Patent JP2009221199
Kind Code:
A
Abstract:

To provide a liquid formulation capable of continuously blocking bitter taste caused by sulfodehydroabietic acid.

The liquid formulation includes a mixture of sodium citrate, crospovidon and liquefied cyclodextrin. It is preferable that the weight ratio of the mixture of sodium citrate, crospovidon and liquefied cyclodextrin, which is an excipient, is 0.2:0.5-0.6:1 based on 1 pt.wt. sulfodehydroabietic acid. It is also preferable that the pH is controlled to be 5.0-5.5.


Inventors:
BAE HYUN JU
YANG EUN YEONE
Application Number:
JP2009057198A
Publication Date:
October 01, 2009
Filing Date:
March 10, 2009
Export Citation:
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Assignee:
KWANG DONG PHARMACEUTICAL CO L
International Classes:
A61K31/19; A61K9/08; A61K47/12; A61K47/32; A61K47/40; A61P1/04
Domestic Patent References:
JP2009067790A2009-04-02
JP2008007420A2008-01-17
Foreign References:
WO2005094893A22005-10-13
WO2007011018A12007-01-25
WO2003028716A12003-04-10
Attorney, Agent or Firm:
▲吉▼川 俊雄