Title:
ペルオキシソーム増殖剤活性化受容体修飾因子
Document Type and Number:
Japanese Patent JP2010519308
Kind Code:
A
Abstract:
The present invention is directed to compounds of the structural Formula: wherein: R1 is H or —C1-C3 alkyl; R2 is selected from the group consisting of —H, —C1-C4 alkyl, —C1-C3 alkyl-CF3, phenyl, and pyridinyl; and R3 is selected from the group consisting of —H, —C1-C4 alkyl, —C1-C3 alkyl-O—CH3, —CH2-cyclopropyl, CH2—C═CH2, —CH2CH2-(2-F-phenyl), and phenyl substituted with from 1 to 2 fluorines; provided that when R1 and R2 are each H, then R3 is selected from the group consisting of —C1-C4 alkyl, —C1-C3 alkyl-O—CH3, —CH2-cyclopropyl, —CH2—C═CH2, —CH2CH2-(2-F-phenyl), and phenyl substituted with from 1 to 2 fluorines; or stereoisomers and pharmaceutically acceptable salts thereof.
Inventors:
Lance Allen Pfeiffer
Ma Tianway
Nathan Bryan Mantro
Laura Frey Michael
Phase Mambo Mokube
Charzad Montrose-Laffiza Day
Ma Tianway
Nathan Bryan Mantro
Laura Frey Michael
Phase Mambo Mokube
Charzad Montrose-Laffiza Day
Application Number:
JP2009550963A
Publication Date:
June 03, 2010
Filing Date:
February 12, 2008
Export Citation:
Assignee:
Eli Lilly and Company
International Classes:
C07D249/12; A61K31/4196; A61K31/4439; A61P3/04; A61P3/06; A61P3/10; A61P9/00; A61P9/10; A61P29/00; A61P43/00; C07D401/06
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Masahiro Nitta
Kure Hidenori
Samejima Mutsumi
Masahiro Nitta
Kure Hidenori