Title:
PERSONAL DENTAL CARE PRODUCT FOR CARIES TREATMENT
Document Type and Number:
Japanese Patent JP2022106703
Kind Code:
A
Abstract:
To provide novel dental care products comprising self-assembling peptides that are capable of undergoing self-assembly at a certain pH for use in dental care, e.g., preventing and/or treating a tooth lesion such as a caries lesion, remineralizing a tooth surface or increasing smoothness or shine, or for increasing hardness of a tooth surface.SOLUTION: There is provided a dental care product for use in treating or preventing a tooth lesion and/or in remineralizing a tooth surface, comprising: (i) self-assembling peptides that are capable of undergoing self-assembly at a pH below 7.5, the self-assembling peptides being present in the dental care product in monomeric form; and (ii) a pharmaceutically acceptable main agent. The dental care product is applied to a plurality of teeth of a subject independent of diagnosis of caries, preferably active caries, and after application, the self-assembling peptides are present in monomeric state for at least 1 minute.SELECTED DRAWING: None
Inventors:
MICHAEL HUG
DOMINIKUS AMADEUS LYSEK
DOMINIKUS AMADEUS LYSEK
Application Number:
JP2022054875A
Publication Date:
July 20, 2022
Filing Date:
March 30, 2022
Export Citation:
Assignee:
CREDENTIS AG
International Classes:
A61K38/03; A21D2/24; A23G3/34; A23G3/44; A23G4/14; A23L33/18; A61K8/64; A61K9/48; A61P1/02; A61Q11/00
Domestic Patent References:
| JP2015526438A | 2015-09-10 |
Foreign References:
| WO2015044268A1 | 2015-04-02 |
Other References:
BRUNTON P A: "TREATMENT OF EARLY CARIES LESIONS USING BIOMIMETIC SELF-ASSEMBLING PEPTIDES--A CLINICAL SAFETY TRIAL", BRITISH DENTAL JOURNAL, vol. VOL:215, NR:4, JPN5019004481, August 2013 (2013-08-01), pages 1 - 6, ISSN: 0005029979
Attorney, Agent or Firm:
Yamato Kento
Norifumi Tomita
Fumio Inai
Manami Sasakura
Norifumi Tomita
Fumio Inai
Manami Sasakura
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