PHARMACEUTICAL COMPOSITION OF CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) INHIBITOR

Title:

PHARMACEUTICAL COMPOSITION OF CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) INHIBITOR

Document Type and Number:

Japanese Patent JP2011052006

Kind Code:

A

Abstract:

To provide a composition including a crystalline cholesteryl ester transfer protein (CETP) inhibitor with increased biological availability.

The pharmaceutical composition includes the crystalline cholesteryl ester transfer protein (CETP) inhibitor and a water-insoluble concentration-elevating additive. The crystalline CETP may be S-[2-([[1-(2-ethylbutyl)cyclohexyl]carbonyl]amino)phenyl]2-methylpropanethioate and the concentration-elevating additive may use crospovidone.

Inventors:

SUNAMI MASAKI
SERIGAYA TAKANORI

Application Number:

JP2010252215A

Publication Date:

March 17, 2011

Filing Date:

November 10, 2010

Export Citation:

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Assignee:

JAPAN TOBACCO INC

International Classes:

A61K31/265; A61K31/16; A61K31/167; A61K47/32; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P9/12

Domestic Patent References:

JPH11222428A	1999-08-17
JP2003026607A	2003-01-29
JP2002509886A	2002-04-02
JP2006520808A	2006-09-14

Foreign References:

WO2002092094A1

2002-11-21

Attorney, Agent or Firm:

Takashima Ichi
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Kenji Yamamoto
Murata Miyuki

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