Title:
PHARMACEUTICAL COMPOSITION CONTAINING AZILSARTAN AND AMLODIPINE AND METHOD FOR PRODUCING THE SAME
Document Type and Number:
Japanese Patent JP2020090471
Kind Code:
A
Abstract:
To provide a pharmaceutical composition that maintains stable physical properties during the production and even after the distribution, and a method for producing the same.SOLUTION: A stabilized pharmaceutical composition contains azilsartan, amlodipine or a salt thereof, and an anti-oxidizing agent or trehalose; particularly, the pharmaceutical composition contains stearic acid in a granule of the azilsartan, and a powder or granule of the amlodipine is a mixture with magnesium stearate, and is in the form of a monolayer tablet.SELECTED DRAWING: Figure 1
Inventors:
YOSHIZAWA KAZUAKI
MATSUDA RYO
JO TAKAAKI
MATSUDA RYO
JO TAKAAKI
Application Number:
JP2018230076A
Publication Date:
June 11, 2020
Filing Date:
December 07, 2018
Export Citation:
Assignee:
NIPRO CORP
International Classes:
A61K31/4245; A61K9/26; A61K31/4422; A61K47/12; A61K47/14; A61K47/22; A61K47/26; A61P9/12; A61P43/00
Domestic Patent References:
| JP2012525323A | 2012-10-22 | |||
| JP2012515768A | 2012-07-12 | |||
| JP2008543728A | 2008-12-04 | |||
| JPH0753373A | 1995-02-28 |
Attorney, Agent or Firm:
Shinki Global IP Patent Corporation