Title:
治療上有効な成分の長期放出/持続放出のための医薬組成物
Document Type and Number:
Japanese Patent JP2006508891
Kind Code:
A
Abstract:
A pharmaceutical composition useful for sustained/extended release of a therapeutically active ingredient to an environment of use, said composition comprises a tablet core composition consists of a therapeutically active ingredient that is weakly acidic in nature and has a limited solubility in the aqueous environment, said the therapeutically active ingredient is in immediate contact with the agents that are capable of improving the solubility of the agent within the core, for e.g., by changing the micro environmental pH of the core and the tablet core is surrounded by a release rate controlling membrane consisting of a semi-permeable membrane forming polymer, permeable membrane forming polymer, and at least one plasticizer capable of modulating the film formation properties of the polymers.
Inventors:
Sanjay, Garg
Rajan, Kumar, Belma
Chaman, Lal, Cowl
Rajan, Kumar, Belma
Chaman, Lal, Cowl
Application Number:
JP2003563519A
Publication Date:
March 16, 2006
Filing Date:
March 22, 2002
Export Citation:
Assignee:
Council of Scientific and Industrial Research
International Classes:
A61K9/22; A61K9/00; A61K9/30; A61K9/32; A61K9/36; A61K31/18; A61K31/192; A61K31/196; A61K31/216; A61K31/341; A61K31/40; A61K31/405; A61K31/43; A61K31/433; A61K31/56; A61K31/603; A61K31/606; A61K31/616; A61K31/64; A61K47/02; A61K47/04; A61K47/10; A61K47/12; A61K47/14; A61K47/18; A61K47/26; A61K47/32; A61K47/34; A61K47/38; A61K47/44; A61P1/04; A61P3/06; A61P3/10; A61P7/10; A61P9/12; A61P29/00; A61P31/04; A61K9/20; A61K9/28
Domestic Patent References:
| JPH01128927A | 1989-05-22 | |||
| JPS5029729A | 1975-03-25 | |||
| JPS6323814A | 1988-02-01 | |||
| JPH08501081A | 1996-02-06 | |||
| JPH07508762A | 1995-09-28 | |||
| JP2001501642A | 2001-02-06 | |||
| JPH021405A | 1990-01-05 | |||
| JPH02174713A | 1990-07-06 | |||
| JPH11506774A | 1999-06-15 | |||
| JPS5519257A | 1980-02-09 | |||
| JPH09104620A | 1997-04-22 |
Foreign References:
| WO1999047125A1 | 1999-09-23 | |||
| WO2001032149A1 | 2001-05-10 | |||
| WO2001074336A1 | 2001-10-11 |
Attorney, Agent or Firm:
Kenji Yoshitake
Yukitaka Nakamura
Konno Akio
Noritaka Yokota
Takeshi Katata
Yukitaka Nakamura
Konno Akio
Noritaka Yokota
Takeshi Katata