Title:
腎疾患の予防及び治療用医薬組成物
Document Type and Number:
Japanese Patent JP4418753
Kind Code:
B2
Abstract:
The present invention relates to a composition for prevention and treatment of kidney diseases comprising one or more effective component(s) of a PAR-2 activating agent which is able to activate PAR-2 and a pharmaceutically acceptable carrier. The present invention further relates to a method for prevention and treatment of kidney diseases comprising administration of a composition for prevention and treatment of kidney diseases containing a PAR-2 activating agent which is able to activate PAR-2 to patients suffering from kidney diseases, and also relates to the use of a PAR-2 activating agent which is able to activate PAR-2 for the manufacture of a composition for prevention and treatment of kidney diseases. The present invention furthermore relates to a method for screening an effective ingredient for prevention and treatment of kidney diseases comprising screening of the activating action of the test substance to PAR-2.
Inventors:
Takashi Nakagawa
Hiroyuki Ishiwata
Toshiaki Takizawa
Toru Sugae
Yasushi Wada
Junichi Kawagoe
Hiroyuki Ishiwata
Toshiaki Takizawa
Toru Sugae
Yasushi Wada
Junichi Kawagoe
Application Number:
JP2004539577A
Publication Date:
February 24, 2010
Filing Date:
September 30, 2003
Export Citation:
Assignee:
Kowa Co., Ltd.
International Classes:
A61K38/00; A61K38/08; A61K38/48; A61P13/12; G01N33/15; G01N33/50; G01N33/68
Other References:
Int. J. Immunotherapy,1997年,Vol.XIII(3/4),p.79-83
Int. J. Immunotherapy,1997年,Vol.XIII(3/4),p.97-103
Am J Physiol Renal Physiol,2002年,Vol.282,p.F891-F897
Int. J. Immunotherapy,1997年,Vol.XIII(3/4),p.97-103
Am J Physiol Renal Physiol,2002年,Vol.282,p.F891-F897
Attorney, Agent or Firm:
Norio Saeki