Title:
抗癌剤投与に伴う末梢神経障害抑制用医薬組成物
Document Type and Number:
Japanese Patent JP4208036
Kind Code:
B1
Abstract:
The invention aims at providing mainly a pharmaceutical composition for inhibiting peripheral neuropathy caused y the administration of an anticancer agent. The invention relates to a pharmaceutical composition for inhibiting peripheral neuropathy caused by the administration of an anticancer agent which composition contains as the active ingredient a compound selected from the group consisting of (±)- 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid, (+) -1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole -1-acetic acid, and (-)-1,8-diethyl-1,3,4,9-tetrahydropyrano- [3,4-b]-indole-1-acetic acid or a pharmaceutically acceptable salt thereof.
Inventors:
Takai Okui
Application Number:
JP2008521731A
Publication Date:
January 14, 2009
Filing Date:
April 25, 2008
Export Citation:
Assignee:
NIPPON SHINYAKU CO.,LTD.
International Classes:
A61K31/407; A61P25/02; C07D491/052
Other References:
高橋利明,抗癌剤投与によるneuropathic painに対するCOX-2阻害薬の臨床応用,Pharma Medica,2006年,Vol.24, No.2,p.79-83
川合真一,薬物療法に関する最近の進歩 選択的COX-2阻害薬の新展開,日本臨床,2002年,Vol.60, No.12,p.2370-2377
川合真一,薬物療法に関する最近の進歩 選択的COX-2阻害薬の新展開,日本臨床,2002年,Vol.60, No.12,p.2370-2377
Attorney, Agent or Firm:
Naoto Shimizu
Toshiyuki Nakato
Toshiyuki Nakato