PHARMACEUTICAL COMPOSITION FOR TREATMENT OF ASTHMA

Japanese Patent JP2010138184

A

To provide a formulation for the treatment of asthma having desirable solubility, stability, low toxicity, accurate dosage, correct particle size and/or compatibility with a usual valve assembly of a dosage-metering inhaler and not containing CFC (chlorofluorocarbon), and a method for producing the same.

An aerosolized formulation for the treatment of asthma (which contains mometasone furoate and formoterol fumarate) and the method for preparing the same are disclosed. The invention relates to a process for producing the nontoxic formulation that does not substantially contain CFC and possesses improved stability and compatibility with medicines and is relatively easily produced. The formulation is produced according to an ordinary procedure in the art for other aerosol compositions. Typically, all components other than this atomizing agent are mixed and introduced in an aerosol can.

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SEQUEIRA JOEL A
SHARPE STEFAN A
HART JOHN L

JP2010036706A

June 24, 2010

February 22, 2010

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SCHERING CORP

A61K9/12; A61K9/00; A61K9/72; A61K9/70; A61K31/00; A61K31/167; A61K31/573; A61K31/58; A61K47/06; A61K47/12; A61K47/24; A61K47/26; A61M13/00; A61P11/00; A61P11/06; A61P29/00; A61P37/08

JPH06511235A	1994-12-15
JP2000503673A	2000-03-28

WO2000051591A1

2000-09-08

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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