Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
PHARMACEUTICAL PREPARATION USEFUL AS SUBSTITUTE FOR MEDICINAL HORMONE IN HUMAN COMPRISING STEROID HAVING ANTIOXIDANT ACTION
Document Type and Number:
Japanese Patent JPH09100292
Kind Code:
A
Abstract:

To obtain the subject preparation useful as a substitute, etc., for human medicinal hormones by using 17α-estradiol, its chemically modified derivative, an ester of the 17α-estradiol, its chemically modified derivative, etc.

This pharmaceutical preparation is compounded by using 17α- estradiol, its chemically modified derivative, an ester of the 17α-estradiol or its chemically modified derivative and is capable of suppressing activities of reactive oxygen species(ROS), oxygen free radicals and other radical forms capable of playing an important role when producing various cytotoxicities by actions of the 17α-estradiols having antioxidant actions and useful for treatment, etc., of human hormone substitutes using estrogens without administration of a high dose and/or administration of a substance for a long period. Thereby, total cholesterol and triglycerides in blood are reduced for prevention, treatment, etc., of atherosclerosis, etc.


Inventors:
Oettel, Michael
Roemer, Wolfgang
Huebler, Dr. Doris
Schroeder, Jens
Schwarz, Sigfrid
Droescher, Dr. Peter
Application Number:
JP1996000178141
Publication Date:
April 15, 1997
Filing Date:
July 08, 1996
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
JENAPHARM GMBH
International Classes:
A61K31/565; A61K31/567; A61P9/00; A61P9/10; A61P25/08; A61P29/00; C07J1/00; (IPC1-7): C07J1/00; A61K31/565
Attorney, Agent or Firm:
渡辺 望稔 (外1名)