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Title:
エストラ-1,3,5(10)-トリエン誘導体を含有する医薬製剤
Document Type and Number:
Japanese Patent JP4023820
Kind Code:
B2
Abstract:
The invention concerns pharmaceutical preparations containing estra-1,3,5(10)-triene derivatives as active ingredients which carry a group of the general formulaat their C3 position whereinR is a R<1>R<2>N group whereinR<1 >and R<2 >are independent of each other and represent a hydrogen atom, a C1-C5 alkyl radical or, together with the N atom, a polymethylene imino radical containing 4 to 6 C atoms, or a morpholino radical.The preparations according to the invention can be used for hormonal contraception and for hormon replacement therapy (HRT). They exhibit a low hepatic estrogenity.

Inventors:
Elgar, Walter
Schwarz, Sigfried
Zieman, Hans-Youahim
Radersen, Goodron
Schneider, Burgit
Application Number:
JP50689996A
Publication Date:
December 19, 2007
Filing Date:
July 03, 1995
Export Citation:
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Assignee:
Schering Acting Zell Shaft
International Classes:
A61K31/56; A61K31/565; A61K31/58; A61P5/00; A61P5/18; A61P5/24; A61P13/08; A61P15/12; A61P15/18; A61P35/00; C07J41/00; C07J43/00; C07J53/00
Domestic Patent References:
JP5032161A
JP5032160A
Foreign References:
DD114806C
DE1949095A1
DE2426778A1
GB1398026A
GB1312218A
Other References:
J.Med.Chem.,(1994),37(2),p.219-21
Pharmazie,(1980),35(1),p.45-7
Pharmazie,(1975),30(1),p.17-21
Pharmazie,(1975),30(1),p.52-3
Z.Chem.,(1974),14(1),p.15-6
Attorney, Agent or Firm:
Noboru Fujimoto