Title:
PHARMACEUTICAL TABLETS CONTAINING APREPITANT AS ACTIVE INGREDIENT
Document Type and Number:
Japanese Patent JP2019073488
Kind Code:
A
Abstract:
To provide pharmaceutical tablets containing aprepitant as active ingredient which exert rapid elution equivalent to capsule formulations.SOLUTION: A pharmaceutical tablet containing aprepitant as an active ingredient and having excellent elution can be provided by using as an excipient a pharmaceutical tablet containing mannitol. Preferably, the mannitol is applied as excipient granules previously granulated together with a disintegrant and the like. Preferably, the aprepitant is applied in a solid dispersion with a water soluble polymer carrier.SELECTED DRAWING: None
Inventors:
NAKAMURA TAKANORI
Application Number:
JP2017202269A
Publication Date:
May 16, 2019
Filing Date:
October 19, 2017
Export Citation:
Assignee:
NIPPON KAYAKU KK
International Classes:
A61K31/5377; A61K9/20; A61K47/26; A61K47/30; A61K47/32; A61K47/38; A61P1/08
Domestic Patent References:
JP2016183195A | 2016-10-20 |
Foreign References:
US20110009362A1 | 2011-01-13 | |||
WO2013081044A1 | 2013-06-06 | |||
WO2016053227A1 | 2016-04-07 |