Title:
PHARMACEUTICALLY ACTIVE SULFONYL AMINO ACID DERIVATIVE
Document Type and Number:
Japanese Patent JP2012111777
Kind Code:
A
Abstract:
To provide sulfonyl amino acid derivatives of formula (I) notably for use as pharmaceutically active compounds, and pharmaceutical formulations containing such sulfonyl amino acid derivatives.
The sulfonyl amino acid derivatives are efficient inhibitors of a JNK (Jun-Kinase) pathway, particularly efficient inhibitors of JNK 2 and 33. Novel sulfonyl amino acid derivatives expressed by formula (I) and methods for preparing them are further provided.
Inventors:
ARKINSTALL STEPHEN
HALAZY SERGE
CHURCH DENNIS
CAMPS MONTSERRAT
RUECKLE THOMAS
GOTTELAND JEAN-PIERRE
BIAMONTE MARCO
HALAZY SERGE
CHURCH DENNIS
CAMPS MONTSERRAT
RUECKLE THOMAS
GOTTELAND JEAN-PIERRE
BIAMONTE MARCO
Application Number:
JP2012033338A
Publication Date:
June 14, 2012
Filing Date:
February 17, 2012
Export Citation:
Assignee:
MERCK SERONO SA
International Classes:
C07D333/34; A61K31/18; A61K31/38; A61K31/381; A61K31/44; A61K31/4436; A61K31/454; A61P1/04; A61P9/10; A61P11/06; A61P19/02; A61P25/00; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P29/00; A61P31/04; A61P35/00; A61P37/02; A61P37/06; A61P43/00; C07C311/46; C07D409/12; C07D409/14; C07C333/00
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Suzuki Keiyasu
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Suzuki Keiyasu