Title:
アミン及びアミノ酸のフェニル-N-アシル誘導体、それらの調製法、それらの製薬組成物及び使用
Document Type and Number:
Japanese Patent JP5384096
Kind Code:
B2
Abstract:
The present invention relates to novel phenyl-N-acyl derivatives of biogenic amines and amino acids of general formula (I) as cyclooxynease inhibitors, possessing analgetic and anti-inflammatory properties and devoid of side effects in particular ulcerogeneity and pro-spasmodic actions, as well as capability to potentiate effect of other analgetics, and possessing in addition antihypoxic, antidepressant and anti-Parkinsonistic action; as well as to the processes for the preparation novel and known phenyl-N-acyl derivatives of biogenic amines, to a pharmaceutical composition and to an agent comprising compounds of general formula (I) as well as to use thereof and a method of treating.
Inventors:
Nevolcin Vladimir Evgenievich
Cromova Tatiana Alexandrovna
Seltshina Galina Alexandrovna
Kovaleva Violetta Leonodochna
Cromova Tatiana Alexandrovna
Seltshina Galina Alexandrovna
Kovaleva Violetta Leonodochna
Application Number:
JP2008502938A
Publication Date:
January 08, 2014
Filing Date:
March 24, 2006
Export Citation:
Assignee:
Obschestvos Oglationnoi Otovetvennostillille "Fermenter Prises"
International Classes:
C07C233/11; A61K31/165; A61K31/198; A61K31/223; A61P25/04; A61P25/08; A61P25/16; A61P25/24; A61P29/00; A61P43/00; C07C231/02; C07C233/22; C07C233/48; C07C233/51; C07C235/34
Domestic Patent References:
| JP57193437A | ||||
| JP9511246A | ||||
| JP2004509974A | ||||
| JP11127894A | ||||
| JP62143698A | ||||
| JP57145891A | ||||
| JP54016402A |
Foreign References:
| WO2004031129A1 | ||||
| WO1998046286A1 | ||||
| WO1997023202A1 | ||||
| WO2001066528A1 |
Other References:
TETRAHEDRON LETTERS,2001年,Vol.42, No.38,P.6659-6662
Bioorgnic and Medicinal Chemistry Letters ,2001年,Vol.11, No.11,P.1441-1444
Journal of Biomedical Materials Research,1998年,Vol.41, No.3,P.443-454
BIOMATERIALS,2000年,Vol.21, No.23,P.2371-2378
CROATICA CHEMICA ACTA ,2001年,Vol.74, No.4,P.757-762
Journal of Medicinal Chemistry,1997年,Vol.40, No.8,P.1186-1194
Bioorgnic and Medicinal Chemistry Letters ,2001年,Vol.11, No.11,P.1441-1444
Journal of Biomedical Materials Research,1998年,Vol.41, No.3,P.443-454
BIOMATERIALS,2000年,Vol.21, No.23,P.2371-2378
CROATICA CHEMICA ACTA ,2001年,Vol.74, No.4,P.757-762
Journal of Medicinal Chemistry,1997年,Vol.40, No.8,P.1186-1194
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama