Title:
PHENYL ACETIC ACID DERIVATIVES AND HYPERLIPIDEMIA TREATING AGENT CONTAINING SAME AS EFFECTIVE COMPONENT
Document Type and Number:
Japanese Patent JPS51125245
Kind Code:
A
Abstract:
The invention provides novel phenylacetic acid derivatives of the formula: in which X and Y are the same or different and each represents halogen and R represents hydroxyl, alkoxy of 1 to 4 carbon atoms, a radical of formula R1-NH-CnH2n-O-, in which n is an integer from 1 to 4 and R1 is hydrogen or an alkanoyl radical R2CO-, in which R2 is alkyl of 1 to 4 carbon atoms, a radical of formula R4NH-, in which R4 is hydrogen or -CmH2mOH, where m is an integer from 1 to 3, or a radical of formula: +TR -OCmH2m-COOR2 or -O(CH2)p-Z radical, where n, m and R2 have the meanings given above, p is 0 or 1, and Z is a saturated or unsaturated ring with 6 ring atoms, one of which can be nitrogen, and which can carry from 1 to 3 methyl radicals, and the addition salts which such a derivative which contains a salifiable basic group forms with pharmaceutically acceptable acids and a process for their preparation. These compounds are useful as hypolipaemic and hypocholesterolaemic agents.
Inventors:
ANRI NAAJIE
DON PIEERU RUNE RUSHIAN JIYUUD
FUIRITSUPU MISHIEERU JIYATSUKU
JIYAN MARII RUI YUUJIINU ROJIE
DON PIEERU RUNE RUSHIAN JIYUUD
FUIRITSUPU MISHIEERU JIYATSUKU
JIYAN MARII RUI YUUJIINU ROJIE
Application Number:
JP107576A
Publication Date:
November 01, 1976
Filing Date:
January 05, 1976
Export Citation:
Assignee:
SYNTHELABO
International Classes:
A61K31/165; A61K31/19; A61K31/21; A61K31/215; C07C51/00; C07C59/68; C07C67/00; C07C213/00; C07C219/10; C07C231/00; C07C235/20; C07C235/34; C07D211/46; C07C69/736; C07D213/30; C07D317/24; C07D317/34; (IPC1-7): A61K31/165; A61K31/19; A61K31/215; A61K31/335; A61K31/435; C07C65/13; C07C69/76; C07C93/20; C07C103/22; C07C103/78; C07D213/30; C07D295/00; C07D317/24