Title:
フェニル酢酸誘導体、その製造方法および用途
Document Type and Number:
Japanese Patent JP4661595
Kind Code:
B2
Abstract:
The present invention relates to the compound represented by formula (I)
(wherein R 1 and R 2 is hydrogen atom, C1-8 alkyl etc.; R 3 is C1-8 alkyl which may be substituted with 1 to 3 halogen atom(s), phenyl; R 4 is hydrogen atom etc. ; R 5 and R 6 is hydrogen atom, CI-8 alkyl etc.; X is sulfur atom or oxygen atom etc.; ringA is cyclic group which may have a substituent(s).), or a salt thereof Toxicity of the compound represented by formula (I) is very low, and it is safe enough to use as a pharmaceutical agent and since it has PPAR ´ agonistic activity, it is useful as preventive and/or therapeutic agent for glucose lipid metabolic disorder, hypertension, circulatory diseases etc.
Inventors:
Shinya Kusuda
Nakayama Kosuke
Hisao Tajima
Takahiko Sakamoto
Nakayama Kosuke
Hisao Tajima
Takahiko Sakamoto
Application Number:
JP2005514140A
Publication Date:
March 30, 2011
Filing Date:
September 21, 2004
Export Citation:
Assignee:
Ono Pharmaceutical Co., Ltd.
International Classes:
C07D263/32; A61K31/421; A61K31/422; A61K31/426; A61K31/427; A61K31/4439; A61K31/454; A61K31/4725; A61K31/496; A61P3/04; A61P3/06; A61P3/10; A61P9/00; A61P9/10; A61P9/12; A61P9/14; A61P17/00; A61P43/00; C07D277/24; C07D413/04; C07D413/10; C07D417/04; C07D417/12
Foreign References:
| WO1999046232A1 | 1999-09-16 | |||
| WO2003072102A1 | 2003-09-04 |
Attorney, Agent or Firm:
Kunihisa Landlord
Atsushi Hayashi
Atsushi Hayashi