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Title:
PHENYLCLOHEXANE DERIVATIVE
Document Type and Number:
Japanese Patent JPS57122041
Kind Code:
A
Abstract:

NEW MATERIAL:A phenylcyclohexane derivative of formula I(R1 is H, hydroxyl group or alkoxyl; R2 is H, aminoalkyl, alkoxylcarbonylalkyl or aminocarbonylalkyl; R3 is oxo, hydroxyl group, alkylcarbonylamino, alkycarbonyloxy, aminoalkylcarbonyloxy, etc.; R4 is H, aminoalkyl, morpholino or morpholinoalkyl; however, R3 and R4 are not H at the same time).

EXAMPLE: 2-Ethoxycarbonylmethyl-6-morpholino-2-phenylcyclohexanone.

USE: Useful as a medicine having inhibitory action on blood platelet aggregation, inhibitory action on contraction of extirpated intestines and anti-inflammatory and analgesic actions.

PROCESS: Either one of R2 or R4 or both are introduced into a phenylcyclohexane of formula II as a starting raw material by the well-known method to give the aimed compound of formulaI (R3 is oxo group).


Inventors:
FUJIMURA HAJIME
HORI MIKIO
TATSUOKA TOSHIO
OKITSU MITSUTO
IMAO KAYOKO
MORITA MINORU
Application Number:
JP849381A
Publication Date:
July 29, 1982
Filing Date:
January 21, 1981
Export Citation:
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Assignee:
SUNTORY LTD
International Classes:
C07D295/08; A61K31/135; A61K31/16; A61K31/165; A61K31/215; A61K31/27; A61K31/445; A61K31/535; A61K31/5375; A61P7/02; A61P25/04; A61P29/00; C07C67/00; C07C69/03; C07C69/73; C07C213/00; C07C215/42; C07C215/64; C07C217/12; C07C217/74; C07C219/24; C07C225/18; C07C227/00; C07C229/08; C07C229/12; C07C229/34; C07C233/11; C07C233/23; C07C233/32; C07C233/38; C07C233/41; C07C235/34; C07C235/40; C07C235/78; C07C235/82; C07C237/20; C07C237/22; C07C237/24; C07D295/04; C07D295/12; C07D295/14; (IPC1-7): A61K31/135; A61K31/165; A61K31/27; A61K31/445; C07C69/03; C07C69/73; C07C91/23; C07C91/30; C07C93/02; C07C93/14; C07C93/24; C07C97/10; C07C101/18; C07C103/22; C07C103/34; C07D295/04
Domestic Patent References:
JPS51138680A1976-11-30
JPS50157342A1975-12-19
Foreign References:
US4150135A1979-04-17



 
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