Title:
PHOSPHORYLCHOLINE-BASED AMPHIPHILIC SILICONES FOR MEDICAL APPLICATIONS
Document Type and Number:
Japanese Patent JP2016053165
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide amphiphilic biomimetic phosphorylcholine-containing silicone compounds for use in both topical and internal applications as active functional components in medical device ophthalmic lenses, ophthalmic lens care solutions, liquid bandages, wound dressings, and lubricious and anti-thrombogenic coatings.SOLUTION: The invention provides polymerizable or non-polymerizable silicone compounds which comprise a silicone moiety having a weight average molecular weight of 1000 to 1500000 Daltons and include zwitterionic phosphorylcholine groups such as compounds represented by formula (I). The invention also provides polymers derived from the compounds, and medical devices using the polymers.SELECTED DRAWING: None
Inventors:
JAMES PARAKKA
ANANTH V IYER
WANG ANFENG
JIANG XUWEI
TIAN YUAN
WARD ROBERT
ANANTH V IYER
WANG ANFENG
JIANG XUWEI
TIAN YUAN
WARD ROBERT
Application Number:
JP2015187026A
Publication Date:
April 14, 2016
Filing Date:
September 24, 2015
Export Citation:
Assignee:
DSM IP ASSETS BV
International Classes:
C08F30/08; A61F2/16; A61L15/16; A61L27/00; A61L31/00; C07F7/18; C07F9/09; C07F19/00; G02C7/04
Domestic Patent References:
| JPS63277246A | 1988-11-15 |
Attorney, Agent or Firm:
Ikeda adult
Kazuhiro Yamaguchi
Masakazu Noda
Yoshinori Shimizu
Kazuhiro Yamaguchi
Masakazu Noda
Yoshinori Shimizu