Title:
【発明の名称】光反応性グリコサミノグリカン、架橋グリコサミノグリカン及びそれらの製造方法
Document Type and Number:
Japanese Patent JP2855307
Kind Code:
B2
Abstract:
Photocurable glycosaminoglycan (GAG) derivatives and crosslinked glycosaminoglycans, which are highly safe and biocompatible, a method of preparing such photocurable GAG derivatives readily moldable by casting using a solvent when desired, by which method unreacted substances causative of adverse effects can be readily eliminated, and a method of producing the crosslinked GAGs and medical materials based on the photocurable GAG derivatives or crosslinked GAGs are provided. The photocurable GAG derivatives comprise a glycosaminoglycan and a photoreactive compound bound thereto and can be produced, for example, by subjecting hydroxyl or carboxyl groups of the glycosaminoglycan to esterification reaction or amidation reaction, respectively, with the photoreactive compound. The crosslinked GAGs are derived from the photocurable GAG derivatives by intermolecular crosslinking of the photoreactive compound bound thereto.
Inventors:
MATSUDA TAKEHISA
MINUU JARIRI MOGADAMU
SAKURAI KATSUKYO
MINUU JARIRI MOGADAMU
SAKURAI KATSUKYO
Application Number:
JP35544192A
Publication Date:
February 10, 1999
Filing Date:
December 21, 1992
Export Citation:
Assignee:
SEIKAGAKU KOGYO KK
International Classes:
A61K31/715; A61K31/726; A61K31/727; A61K31/737; A61K47/48; A61K47/36; A61L27/00; A61L27/20; A61L31/04; A61L33/00; A61L33/08; A61L33/10; A61P43/00; C08B37/00; C08B37/08; C08B37/10; C08F251/00; C08L5/00; C08L5/08; C08L5/10; C08L51/02; (IPC1-7): C08B37/00; A61K31/725; A61K47/36; A61L27/00; A61L33/00
Attorney, Agent or Firm:
Tadashi Hagino (3 outside)