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Title:
赤外域光による光線力学的治療又は診断剤
Document Type and Number:
Japanese Patent JP5854407
Kind Code:
B2
Abstract:
It is intended to provide a therapeutic and/or diagnostic agent that can be used in photodynamic therapy (PDT) or photodynamic diagnosis (PDD) capable of utilizing infrared-spectrum light such as near-infrared light (NIR), infrared light, or far-infrared light, which attains a deep body penetration. The present invention provides a photodynamic therapeutic or diagnostic agent or a photodynamic therapeutic or diagnostic kit for cancer or infectious disease, comprising: a particle (e.g., a lanthanide particle) that emits upconversion luminescence by infrared-spectrum light such as near-infrared light having a wavelength of 0.7 µm to 2.5 µm; and a photosensitizer (e.g., porphyrin) or a 5-aminolevulinic acid group.

Inventors:
Yuya Yuasa
Shunichiro Ogura
Research Takahashi
Katsuji Inoue
Toru Tanaka
Application Number:
JP2013513917A
Publication Date:
February 09, 2016
Filing Date:
April 27, 2012
Export Citation:
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Assignee:
National University Corporation Tokyo Institute of Technology
SBI Pharma Co., Ltd.
International Classes:
A61K41/00; A61K31/197; A61K31/409; A61K33/24; A61K45/00; A61K49/00; A61P35/00; A61P43/00
Domestic Patent References:
JP2009024115A2009-02-05
Foreign References:
WO2005087196A12005-09-22
Other References:
JPN6014042360; 金子貞男: '"悪性脳腫瘍に対する光線力学的療法-光感受性物質ALAを用いたPDDとPDTを中心に-"' 日本レーザー医学会誌 Vol.29,No.2, 2008, P.135-146
JPN6014042361; 田中徹 外3名: '"世界のALA-PDD、PDT開発状況と応用分野の拡大"' 日本レーザー医学会誌 Vol.30,No.2, 200907, P.198
JPN7014002905; 田中徹: '"5-アミノレブリン酸を用いたPDD、PDTの現状と将来"' 日本泌尿器学会雑誌 Vol.101,No.2, 20100220, P.133
JPN7014002906; 松井誠 外5名: '"オリゴマンノース被膜リポソームは胃癌患者腹腔内マクロファージによって腹膜微小転移巣に高効率に輸送さ' 日本癌学会学術総会記事 Vol.68th, 20090831, P.51
JPN7014002907; 池原譲 外8名: '"オリゴマンノース被膜リポソーム(OML)を用いたがんワクチン送達システム"' 日本癌学会学術総会記事 Vol.65th, 20060828, P.444
Attorney, Agent or Firm:
Masaki Hirota
Seiji Ozawa
Yusaku Tokai
Makoto Horiuchi



 
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