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Title:
フタラジンイソオキサゾールアルコキシ誘導体、その製造方法、薬物組成物および使用
Document Type and Number:
Japanese Patent JP7351590
Kind Code:
B2
Abstract:
The present invention discloses phthalazine isoxazole alkoxy derivatives, a preparation method thereof, a pharmaceutical composition, and a use thereof. The present invention provides a compound represented by Formula I, cis-trans isomers thereof, enantiomers thereof, diastereoisomers thereof, racemates thereof, solvates thereof, hydrates thereof, and pharmaceutically acceptable salts or prodrugs thereof. The compound has an excellent inverse agonist effect with respect to α5-GABAA.

Inventors:
One, Faye
Wu, Chin Hoa
Chin, Yun
Sun, Yong
Lee, Shorei
Application Number:
JP2020572597A
Publication Date:
September 27, 2023
Filing Date:
March 12, 2019
Export Citation:
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Assignee:
Shanghai SIMR Biotechnology Company Limited
Shanghai SIMRD Biotechnology Company Limited
International Classes:
C07D487/04; A61K31/5025; A61K31/5377; A61P21/02; A61P25/00; A61P25/04; A61P25/06; A61P25/28; A61P25/36
Domestic Patent References:
JP2001525802A
Foreign References:
WO2017097217A1
Attorney, Agent or Firm:
Kazunobu Kato