Title:
PHTHALOCYANINE PROBES AND USES THEREOF
Document Type and Number:
Japanese Patent JP2022023175
Kind Code:
A
Abstract:
To provide improved photosensitizing probes based on small molecule conjugates to induce apoptosis in target cells, e.g., diseased cells, in a subject using photodynamic therapy.SOLUTION: The present invention relates to compositions and methods for destroying target cells in a patient using photodynamic therapy. In particular, the present invention provides a photosensitizing agent based on a small molecular weight (<50 kDa) protein or peptide or a small molecule that is conjugated to a phthalocyanine dye, such as IRDye(R) 700DX.SELECTED DRAWING: Figure 1
Inventors:
JOY L KOVAR
Application Number:
JP2021175445A
Publication Date:
February 07, 2022
Filing Date:
October 27, 2021
Export Citation:
Assignee:
RAKUTEN MEDICAL INC
International Classes:
A61K31/695; A61K41/00; A61K45/00; A61K47/62; A61K47/68; A61K51/04; A61K51/08; A61K51/10; A61P9/00; A61P17/00; A61P17/02; A61P17/06; A61P17/10; A61P31/04; A61P35/00; A61P43/00
Attorney, Agent or Firm:
Aoki Atsushi
Shinji Mihashi
Youichi Watanabe
Nakajima Masaru
Tatsunori Ikeda
Kazumi Nakamura
Shinji Mihashi
Youichi Watanabe
Nakajima Masaru
Tatsunori Ikeda
Kazumi Nakamura