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Title:
mGluR5増強因子としてのピペラジン類及びピペリジン類
Document Type and Number:
Japanese Patent JP2009524702
Kind Code:
A
Abstract:
Compounds of Formula I or pharmaceutically acceptable salts or solvates thereof: wherein Ar1, Ar2, A, X, Y, m, n and R1, R2, R3, R4 and R5 are as described in the specification, processes for their preparation, pharmaceutical formulations comprising them and their use in therapy, particularly in the therapy of neurological and psychiatric disorders associated with glutamate dysfunction.

Inventors:
Abdelmalik Surashi
Mesvin Isaac
Jaraj Arora
Dean Gee Brown
Application Number:
JP2008558259A
Publication Date:
July 02, 2009
Filing Date:
January 05, 2007
Export Citation:
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Assignee:
ASTRAZENECA AKTIEBOLAG
International Classes:
C07D211/18; A61K31/381; A61K31/435; A61K31/495; A61K31/496; A61K31/497; A61K31/506; A61K31/551; A61P25/00; A61P25/04; A61P25/08; A61P25/14; A61P25/18; A61P25/20; A61P25/28; A61P25/30; A61P43/00; C07D213/30; C07D213/74; C07D213/85; C07D233/64; C07D241/12; C07D243/08; C07D277/24; C07D295/16; C07D333/16; C07D401/12; C07D409/12; C07D417/12
Domestic Patent References:
JP2001261657A2001-09-26
JP2005502623A2005-01-27
Foreign References:
WO2005030128A22005-04-07
WO2003093236A12003-11-13
WO2006002349A12006-01-05
WO2004089470A22004-10-21
EP0105397A11984-04-18
Attorney, Agent or Firm:
Junji Yuda
Shoji Miwa
Noriyuki Takebayashi
Chika Takagi