Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
PLACEBO GRANULE FOR COATING TEST AND SORTING OF PLACEBO GRANULE
Document Type and Number:
Japanese Patent JPH07270399
Kind Code:
A
Abstract:

PURPOSE: To sorting with a medicinal effect component-containing granule within a short time by using a placebo granule containing a specific ratio of an iron powder with respect to the whole system.

CONSTITUTION: When the content of the iron powder in a placebo granule is 0.1wt.% or less, sorting recovery due to a magnet becomes low and, when 5wt.% or more, the apparent density of the placebo e granule becomes large and the placebo granule is largely different from a medicinal effect component- containing granaule and correct coating evaluation becomes impossible. Therefore, 0.1-5wt.% of the iron powder is added to the whole system. Lactose, starch, a binder, a disintegrator and the iron powder are charged in a kneader by predetermined amts. to be stirred and a predetermined amt. of water is added to the kneader to be kneaded along with those components. The kneaded mixture is supplied to a granulator to be granulated and dried by a fluidized bed dryer to obtain the placebo granule. This granaule and a main medicine- containing granule are mixed in a proper ratio to perform coating. By this method, the placebo granaule can be attracted and removed by a magnet after coating and workability can be enhanced.


Inventors:
MARUYAMA NAOAKI
Application Number:
JP8388494A
Publication Date:
October 20, 1995
Filing Date:
March 30, 1994
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
SHINETSU CHEMICAL CO
International Classes:
G01N33/15; A61K9/16; (IPC1-7): G01N33/15; A61K9/16