To provide a plasma component separator excellent for treating age-related macular degeneration, which has complement activation suppressing ability and blood coagulation system activation suppressing ability, and a blood purifying apparatus by double filtration capable of safe and efficient blood treatment using it.
The plasma component separator 7 is a hollow fiber membrane type plasma component separator 7 in which a hollow fiber membrane is composed of a polysulfone polymer and polyvinylpyrrolidone, the permeability of bovine plasma immunoglobulin G is ≥80% and ≤100%, the permeability of bovine plasma fibrinogen is ≥10% and ≤30%, the liquid surface elevation value of the hollow fiber membrane measured by a capillary-rise method is ≥80mm and ≤120mm when converted to the hollow fiber membrane of an inner diameter 200μm, and the circle conversion rate diameter of the hole diameter of the inner surface of the hollow fiber membrane is 13nm-64nm. In the double filtering blood purifying apparatus using the plasma component separator 7, heating control of the plasma is performed in a plasma introducing circuit connecting a plasma separator 3 and the plasma component separator 7.
COPYRIGHT: (C)2007,JPO&INPIT
ARAKI HIROKO
SAKAKIBARA SHIGEKI
Kyoko Yoshimi
Sanae Goto
Kiyoshi Fujino