Title:
【発明の名称】血漿様溶液
Document Type and Number:
Japanese Patent JPH08511265
Kind Code:
A
Abstract:
An artificial plasma-like substance having at least one water soluble polysaccharide oncotic agent selected from the group consisting of high molecular weight hydroxyethyl starch, low molecular weight hydroxyethyl starch, dextran 40 and dextran 70, and albumin which is buffered by lactate and has a pre-administration pH of between 5 and 6.5 is disclosed. Also disclosed is an artificial plasma-like solution having at least two water soluble polysaccharide oncotic agents one of which is eliminated from the circulation slowly and the other of which is eliminated from the circulation quickly. Supplimentation of the plasma-like solution with certain ions is described. A system for administration of the plasma-like solution to a subject wherein the system comprises a first and second solution each having particular buffers is described. The plasma-like solution including cryoprotective adducts is also disclosed. The use of the plasma-like solution in organ transplant, novel chemotherapy procedures, and tissue, organ and organism cryopreservation are also disclosed.
Inventors:
Seagal Paul E
Sternberg Hull
Waits Harold Dee
Seagal Judith M
Sternberg Hull
Waits Harold Dee
Seagal Judith M
Application Number:
JP50197895A
Publication Date:
November 26, 1996
Filing Date:
June 03, 1994
Export Citation:
Assignee:
Bio time ink
International Classes:
A01N1/02; A61K33/00; A61K9/00; A61K31/00; A61K31/19; A61K31/718; A61K33/06; A61K33/10; A61K33/14; A61K35/14; A61P7/08; (IPC1-7): A61K33/00
Attorney, Agent or Firm:
Shimizu Hatsushi