Title:
ワクチン及び標的としてのプラスモジウムスポロゾイトＮＰＤＰペプチド、新規マラリアワクチン、及びそれに結合する抗体
Document Type and Number:
Japanese Patent JP7278259
Kind Code:
B2
Abstract:
The present invention provides a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1, for example for use in a malaria vaccine. The present invention also provides nucleic acids encoding a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1, compositions comprising a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1 and antibodies binding to a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1. The antibodies according to the present invention bind specifically to P. falciparum sporozoites and may be used in the treatment and/or prevention of malaria.
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Inventors:
Antonio Lanzavecchia
Joshua Hung Yu Tang
Claudia Dobenberger
Brandon Sack
Joshua Hung Yu Tang
Claudia Dobenberger
Brandon Sack
Application Number:
JP2020508071A
Publication Date:
May 19, 2023
Filing Date:
April 19, 2018
Export Citation:
Assignee:
INSTITUTE FOR RESEARCH IN BIOMEDICINE
International Classes:
C07K16/20; A61K39/395; A61K48/00; A61P33/06; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/13; C12N15/63
Other References:
The Journal of Clinical Investigation,Volume. 124, Number 1,pp.140-144
ASTMH 63rd Annual Meeting, November 2-6, 2014,p.491,1607
ASTMH 63rd Annual Meeting, November 2-6, 2014,p.491,1607
Attorney, Agent or Firm:
Tadashige Ito
Koichi Hirota
Tadahiko Ito
Koichi Hirota
Tadahiko Ito
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