Title:
POLYAMIDE AMINE DENDRON LIPID CONTAINING PARAMAGNETIC METAL
Document Type and Number:
Japanese Patent JP2009269855
Kind Code:
A
Abstract:
To provide a paramagnetic metal-containing compound useful as a contrast medium for MRI and a liposome containing the compound.
The polyamide amine dendron lipid containing a paramagnetic metal has a structural formula in which one or more free amino groups in the polyamide amine dendron lipid are bonded through a linker to a paramagnetic metal. The liposome comprises the compound. The contrast medium for MRI comprising the liposome is useful for detecting a tumor site.
Inventors:
KONO KENJI
AOKI ICHIO
AOKI ICHIO
Application Number:
JP2008121573A
Publication Date:
November 19, 2009
Filing Date:
May 07, 2008
Export Citation:
Assignee:
UNIV OSAKA PREFECTURE
NATL INST RADIOLOGICAL SCIENCE
NATL INST RADIOLOGICAL SCIENCE
International Classes:
C07D257/02; A61B5/055; A61K49/00; G01R33/28
Domestic Patent References:
JPS59139390A | 1984-08-10 | |||
JPH04217927A | 1992-08-07 | |||
JP2008510829A | 2008-04-10 | |||
JP2004159504A | 2004-06-10 | |||
JPS59139390A | 1984-08-10 | |||
JPH04217927A | 1992-08-07 |
Attorney, Agent or Firm:
Shintaro Nogawa