Title:
ポリカチオン化合物とその使用
Document Type and Number:
Japanese Patent JP5209302
Kind Code:
B2
Abstract:
Compounds useful in modulating angiogenesis and uses thereof in methods of treating or preventing diseases associated with angiogenesis by administering a polycationic compound; and compositions for use in inhibiting angiogenesis-mediated disorders in mammals including animals and humans are disclosed. Additionally, the combined use of polycations with other anti- angiogenesis agents for the treatment of different angiogenesis-mediated disorders and use of those polycationic compounds with various anti-inflammatory and cytotoxic agents as well as with radio-therapeutic agents in cancer patients to prevent and treat tumor growth and metastasis are described.
Inventors:
Shaker, Musa
Application Number:
JP2007516741A
Publication Date:
June 12, 2013
Filing Date:
June 15, 2005
Export Citation:
Assignee:
Polymedics, ink.
International Classes:
C07C323/36; A61K31/165; A61K31/166; A61K31/167; A61K31/609; A61P1/04; A61P9/10; A61P9/14; A61P15/00; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P27/02; A61P29/00; A61P31/18; A61P35/00; A61P43/00; C07C211/29; C07C219/06; C07C233/68; C07C235/16; C07C235/20; C07C235/50; C07C235/54; C07C235/56; C07C235/60; C07C237/04; C07C237/24; C07C237/36; C07C237/42; C07C243/38; C07C279/12; C07C279/14; C07C323/42; C07C323/44; C07D239/28
Domestic Patent References:
| JP2006521355A |
Other References:
Liu, Dahui; Choi, Sungwook; Chen, Bin; Doerksen, Robert J.; Clements, Dylan J.; Winkler, Jeffrey D.; Klein, Michael L.; De Grado, William F.,Nontoxic membrane-active antimicrobial arylamide oligomers,Angewandte Chemie, International Edition,2004年,43(9),1158-1162
Attorney, Agent or Firm:
Taro Yaguchi
Yasuaki Yamaguchi
Yasuaki Yamaguchi
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