Title:
ＣＤＫ９阻害剤としての多環式アミド系誘導体、その調製方法及び用途
Document Type and Number:
Japanese Patent JP7406008
Kind Code:
B2
Abstract:
A polycyclic amide derivative as a CDK9 inhibitor, and a preparation method therefor and use thereof. The polycyclic amide derivative exhibits an excellent CDK9 enzyme inhibitory activity, and can be used for preparing a medicine for treating cancers, wherein the cancers are especially hematological cancers, including acute myeloid leukemia, multiple myeloma, chronic lymphocytic leukemia, follicular lymphoma and solid tumors including breast cancer, prostate cancer, ovarian cancer, hepatocellular cancer, pancreatic cancer, renal cancer, gastric cancer, colorectal cancer and lung cancer.
Inventors:
Chung Su Xin
Hsieh Cheng
Cheng Mingwue
Lu Xiao Jie
Takashi Go
Hsieh Cheng
Cheng Mingwue
Lu Xiao Jie
Takashi Go
Application Number:
JP2022569624A
Publication Date:
December 26, 2023
Filing Date:
April 30, 2021
Export Citation:
Assignee:
SUZHOU ALPHAMA BIOTECHNOLOGY CO., LTD.
International Classes:
C07D487/04; A61K31/4439; A61P1/16; A61P1/18; A61P11/00; A61P13/08; A61P13/12; A61P15/00; A61P35/00; A61P35/02
Domestic Patent References:
| JP2013521324A | ||||
| JP2018522869A |
Foreign References:
| WO2018090869A1 | ||||
| WO2016010108A1 |
Attorney, Agent or Firm:
TRY International Patent Attorney Corporation
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