POLYMER CROSS-LINKING AGENT AND LIPOSOME OR CELL CROSS-LINKED PRODUCT USING THE CROSS-LINKING AGENT

Title:

POLYMER CROSS-LINKING AGENT AND LIPOSOME OR CELL CROSS-LINKED PRODUCT USING THE CROSS-LINKING AGENT

Document Type and Number:

Japanese Patent JP2007112924

Kind Code:

A

Abstract:

To solve a problem that biological polymer cross-linked products prepared by chemically cross-linking biological polymers such as collagen or gelatin through covalent bonds strongly denaturate proteins or damage cells because of being prepared with the covalent bonds, while the biological polymer cross-linked products have been used as a material for the sustained release of proteins or as a three-dimensional culture carrier to perform the sustained release of protein preparations or the regeneration of biological tissues.

The polymer cross-linking agent having a hydrophobic portion and a hydrophilic portion in one molecule is synthesized and then used to physically cross-link cells, liposomes or cell-liposome mixtures which are lipid aggregates.

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Inventors:

TAGUCHI TETSUSHI
ITO TOMOKO
TANAKA JUNZO

Application Number:

JP2005306847A

Publication Date:

May 10, 2007

Filing Date:

October 21, 2005

Export Citation:

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Assignee:

NAT INST FOR MATERIALS SCIENCE

International Classes:

C08G85/00; A61K47/34; A61K47/42; A61L27/00; C08L101/16

Domestic Patent References:

JP2004196675A	2004-07-15
JP2005508421A	2005-03-31
JP2002540065A	2002-11-26
JP2003510375A	2003-03-18
JP2003524615A	2003-08-19

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