To provide polynucleotides encoding antigenic HIV polypeptides, formulations of immunogenic compositions thereof and uses thereof as well as methods of using these polynucleotides and polypeptide products therefrom for the treatment of acquired immune deficiency syndrome (AIDS).
Provided are polynucleotides encoding immunogenic HIV polypeptides; uses of the polynucleotides in applications including immunization, generation of packaging cell lines, and production of HIV polypeptides; polynucleotides encoding antigenic HIV polypeptides; uses of these polynucleotides and polypeptide products derived therefrom; and isolated wild-type polynucleotides and/or expression cassettes encoding HIV polypeptides (Env, Gag, Pol, Prot, Rt, Int, Vpr, Vpu, Vif, Nef, Tat, Rev and/or combinations and fragments thereof) in a specific embodiment.
BARNETT SUSAN W
LIAN YING
ENGELBRECHT SUSAN
VAN RENSBURG ESTRELITA JANSE
SCRIBA THOMAS JENS
UNIV OF STELLENBOSCH
Takaaki Yasumura
Natsuki Morishita