Title:
POLYPEPTIDE FROM NONTYPEABLE HAEMOPHILUS INFLUENZAE
Document Type and Number:
Japanese Patent JP2012000112
Kind Code:
A
Abstract:
To provide a polypeptide used for developing a vaccine for preventing and/or treating infection caused by nontypeable H.influenzae.
There is provided a polypeptide comprising nontypeable Haemophilus influenzae (NTHi) amino acid sequences. Over 2,500 specific NTHi proteins are disclosed. There are further provided related polypeptides, nucleic acids, antibodies and methods. These can all be used in medicine for treating or preventing disease and/or infection (e.g. otitis media) caused by H. influenzae.
Inventors:
MASIGNANI VEGA
ARICO MARIA
ARICO MARIA
Application Number:
JP2011166505A
Publication Date:
January 05, 2012
Filing Date:
July 29, 2011
Export Citation:
Assignee:
NOVARTIS VACCINES & DIAGNOSTIC
International Classes:
C12N15/09; A61K38/00; A61K39/102; A61P31/04; A61P31/12; C07K14/285; C07K16/12; A61K39/00; C12P21/08; C12Q1/68
Foreign References:
| WO2002083723A2 | 2002-10-24 |
Other References:
JPN6013002328; Ｆｌｅｉｓｃｈｍａｎｎ，Ｒ．Ｄ．ｅｔ ａｌ．: '"Ａｃｃｅｓｓｉｏｎ：Ｕ３２８３５．１［ｇｉ：１５７４４５９］，Ｄｅｆｉｎｉｔｉｏｎ：Ｈａｅｍｏｐｈｉｌｕｓ ｉｎｆｌｕｅｎｚａｅ Ｒｄ ｓｅｃｔｉｏｎ １５０ ｏｆ １６３ ｏｆ ｔｈｅ ｃｏｍｐｌ' ＮＣＢＩ Ｅｎｔｒｅｚ Ｎｕｃｌｅｏｔｉｄｅ［ｏｎｌｉｎｅ］；２９-ＭＡＹ-１９９８ ｕｐｌｏａｄｅｄ，ＮＣＢＩ，［ｒｅｔｒｉｅｖｅｄ ｏｎ １７ Ｊａｎｕａｒｙ ２０１３］
JPN6013002331; Ｉｎｆｅｃｔ．Ｉｍｍｕｎ．，２００３ Ｊｕｎ，７１（６），ｐ．３４５４-６２
JPN6013002331; Ｉｎｆｅｃｔ．Ｉｍｍｕｎ．，２００３ Ｊｕｎ，７１（６），ｐ．３４５４-６２
Attorney, Agent or Firm:
Takeshi Oshio
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