POLYPEPTIDE FOR VACCINATION AGAINST HERPES SIMPLEX VIRUS INFECTED DISEASE

Japanese Patent JP2669594

B2

PURPOSE: To provide a vaccination polypeptide effective in preventing and treating herpes simplex virus types I and II infected diseases.
CONSTITUTION: A vaccination uses a synthetic polypeptide comprising an amino acid sequence which is substantially common to herpes simplex virus envelope glycoproteins gD-1 and gD-2 and represented by the formula: (a) RNH-Met-Ala- Asp-Pro-Asn-Arg-COR'; (b) RNH-Ser -Leu-Lys -Met-Ala -Asp-Pro -Asn-Arg -Phe-Arg -Phe-Arg -Gly-Lys -Asp-Leu -Pro-COR'; (c) RNH-Lys -Tyr-Ala -Leu-Ala -Asp-Ala -Ser-Leu -Lys-Met -Ala-Asp -Pro-Asn -Arg-Phe -Arg-Gly -Lus-Asp -Leu-Pro -Val-Leu -Asp-Gln -Leu-Thr -Asp-COR'; or (d) RNH-Lys-Tyr -Ala-Leu -Ala-Asp-Ala -Met-Leu -Lys-Met -Ala-Asp-Pro -Asn-Arg -Phe-Arg -Gly-Lys -Asp-Leu -Pro-Val -Leu-Asp -Gln-Leu -Thr-Asp=COR' (wherein R is a hydrogen or one or more amino acid residues; and R' is hydroxyl or one or more amino acid residues).

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Gary H. Cohen
Roselin Jei Eisenberg

JP5457294A

October 29, 1997

February 28, 1994

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Competitive Technologies, Inc.

C12Q1/70; A61K39/245; A61P31/12; A61P31/22; C07K1/14; C07K1/22; C07K7/04; C07K7/06; C07K7/08; C07K14/00; C07K14/03; C07K14/035; C07K14/705; C12P21/02; G01N33/53; G01N33/569; G01N33/577; G01N33/68; A61K39/00; C12R1/92; A61K; C07K; (IPC1-7): C07K14/035; C07K7/06; C07K7/08

Shusaku Yamamoto (1 person outside)

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